Table 3 Univariate and multivariate logistic regression analyses for septic shock after admission with sepsis

General demographics

 Age (years), median(IQR)

1.275 (1.197–1.359)

< 0.001

−

 Underlying

3.31 (1.72–6.42)

< 0.001

−

 Body temperature (F)

1.25 (1.12–1.75)

< 0.001

−

 Glasgow Coma Scale

0.737 (0.632–0.86)

< 0.001

−

 Respiratory rate (/min)

1.08 (1.02–1.14)

0.003

−

Laboratory data at PED

 Glucose (mg/dL)

1.01 (1.00–1.02)

0.001

−

 Blood urea nitrogen (mg/dL)

1.08 (1.04–1.11)

< 0.001

−

 Creatinine (mg/dL)

2.97 (1.40–6.27)

< 0.001

−

 Aspartate aminotransferase (U/L)

1.003 (0.999–1.007)

0.05

−

 Potassium (mEq/L)

0.25 (0.14–0.44)

< 0.001

−

 C-reactive protein (mg/L)

1.01 (1.006–1.014)

< 0.001

−

 Procalcitonin (ng/mL)

1.04 (1.02–1.07)

< 0.001

−

 Albumin(g/dL)

0.12 (0.03–0.45)

< 0.001

−

 Platelet (*10³/µL)

1.00 (1.00–1.00)

0.001

−

Hemodynamics

 At PED

 HR (bpm)

0.97 (0.95–0.98)

< 0.001

−

 SBP (mmHg)

0.92 (0.89–0.96)

< 0.001

−

 DBP (mmHg)

0.97 (0.94–1.00)

0.035

−

 HR/SBP (shock index)

6.64 (1.58–25.65)

0.003

 MAP (mmHg)

0.95 (0.91–0.98)

0.002

During the first 24 h after admission

 SBP (mmHg) minimum in 24 h

0.92 (0.90–0.94)

< 0.001

−

 MAP (mmHg) minimum in 24 h

0.90 (0.87–0.93)

< 0.001

−

 DBP (mmHg) minimum in 24 h

0.89 (0.87–0.92)

< 0.001

−

 HR/SBP (shock index) Maximum in 24 h

3.56 (1.64–7.75)

< 0.001

−

 HR/DBP (diastolic shock index) maximum in 24 h

2.28 (1.54–3.36)

< 0.001

−

 DBP/SBP (D/S ratio) minimum in 24 h

0.098 (0.049–0.195)

< 0.001

0.115 (0.052–0.253)

< 0.001