From: Severe hyperlactatemia in the emergency department: clinical characteristics, etiology and mortality
Characteristic | Overall (N = 26,680) | Lactate < 2 mmol/L (N = 15,735) | Lactate 2—3.99 mmol/L (N = 7,680) | Lactate 4—9.99 mmol/L (N = 2,799) | Lactate ≥ 10 mmol/L (N = 466) | p-value |
---|---|---|---|---|---|---|
Treatment in ED | ||||||
Mechanical ventilator | 2,829 (11%) | 1,161 (7.4%) | 902 (12%) | 595 (21%) | 171 (37%) | < 0.01 |
Vasopressor | 2,366 (8.9%) | 823 (5.2%) | 858 (11%) | 556 (20%) | 129 (28%) | < 0.01 |
Disposition type | ||||||
Ward admission | 14,985 (56%) | 9,278 (59%) | 4,305 (56%) | 1,259 (45%) | 143 (31%) | < 0.01 |
ICU admission | 5,372 (20%) | 2,209 (14%) | 1,728 (22%) | 1,168 (42%) | 267 (58%) | < 0.01 |
Discharge | 6,290 (24%) | 4,246 (27%) | 1,641 (21%) | 357 (13%) | 46 (10%) | < 0.01 |
ED Death | 33 (0.1%) | 2 (< 0.1%) | 6 (< 0.1%) | 15 (0.5%) | 10 (2.1%) | < 0.01 |
Mortality | ||||||
48-h mortality | 194 (0.7%) | 15 (< 0.1%) | 43 (0.6%) | 77 (2.8%) | 59 (13%) | < 0.01 |
7-days mortality | 684 (2.6%) | 124 (0.8%) | 201 (2.6%) | 224 (8.0%) | 135 (29%) | < 0.01 |
28-days mortality | 1,506 (5.6%) | 459 (2.9%) | 474 (6.2%) | 401 (14%) | 172 (37%) | < 0.01 |
60-days mortality | 1,807 (6.8%) | 606 (3.9%) | 577 (7.5%) | 447 (16%) | 177 (38%) | < 0.01 |
Others outcome | ||||||
Ever ICU transfer | 7,570 (28%) | 3,415 (22%) | 2,384 (31%) | 1,460 (52%) | 311 (67%) | < 0.01 |
Ever mechanical ventilator | 3,428 (13%) | 1,413 (9.0%) | 1,090 (14%) | 728 (26%) | 197 (42%) | < 0.01 |
Hospital length of stay | 7 (4—13) | 7 (4—13) | 7 (4—13) | 8 (4—15) | 6 (2—12) | < 0.01 |