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Table 3 Diagnostic accuracy of MEWS, SAPS II, SOFA, and APACHE II scores to predict shock in patients with diabetes within 48 h after visiting the ED

From: Comparison of Modified Early Warning Score (MEWS), Simplified Acute Physiology Score II (SAPS II), Sequential Organ Failure Assessment (SOFA), and Acute Physiology and Chronic Health Evaluation II (APACHE II) for early prediction of septic shock in diabetic patients in Emergency Departments

Score

Cutoff

Odds

ratio

Sens

(95% CI)

Spec

(95% CI)

PPV

(95% CI)

NPV

(95% CI)

LR+

(95% CI)

LR-

(95% CI)

AUROC (95% CI)

p-value*

SOFA

≥ 6

43.81 (24.59–77.98)

89.5% (83.5–93.9%)

83.8% (79.8–87.2%)

67.7% (60.7–74.1%)

95.4% (92.7–97.4%)

5.51 (4.38–6.92)

0.13 (0.08–0.20)

0.866 (0.84–0.90)

-

MEWS

≥ 6

2.37 (1.60–3.51)

67.8% (59.7–75.1%)

53.0% (48.0–58.0%)

35.4% (29.9–41.2%)

81.2% (76-85.8%)

1.44 (1.24–1.68)

0.61 (0.47–0.78)

0.604 (0.56–0.65)

0.286

SAPS II

≥ 45

4.92 (3.31–7.33)

61.2% (53.0–69.0%)

75.8% (71.2–79.9%)

48.9% (41.6–56.3%)

83.7% (79.5–87.4%)

2.52 (2.04–3.13)

0.51 (0.42–0.63)

0.685 (0.64–0.73)

0.061

APACHE II

≥ 21

4.02 (2.71–5.94)

57.2% (49.0-65.2%)

75% (70.5–79.2%)

46.5% (39.2–53.9%)

82.2% (77.9–86.0%)

2.29 (1.84–2.85)

0.57 (0.47–0.69)

0.661 (0.62–0.71)

0.909

  1. * P valued compared with SOFA ≥ 6 (p < 0.001)
  2. Data are presented as odds ratio 95% CI: confidence Interval, SD: standard deviation, AUROC: Area under the ROC curve, Sens: sensitivity, Spec: Specificity, PPV: positive predictive values, NPV: negative predictive values and LR: likelihood ratio