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Table 1 Demographic structures of patients, chronic diseases, other findings and their relationship with intubation

From: Can ketamine administration prevent intubation in patients who cannot comply with NIV due to agitation?

 

No intubation

n :46 (56.8%)

Intubation

n:35 (43.2%)

p

Age

75.93 ± 11.39

78.51 ± 12.49

0.336*

Gender

Male

18

39.13%

17

48.57%

0.395+

Female

28

60.87%

18

51.43%

Present clinical situation

Asthma Attack

2

4.35%

0

0.00%

0.503ǂ

Decompensated cardiac failure

19

41,30%

7

20.00%

0.073+

Hypertensive pulmonary edema

4

8.70%

8

22.86%

0.144+

Interstitial lung disease

0

0.00%

1

2.86%

0.890ǂ

COPD Attack

15

32.61%

13

37.14%

0.849

Malignant effusion

one

2.17%

0

0.00%

0.890ǂ

Pneumonia

5

10.87%

6

17.14%

0.625+

Hypertension

38

82.61%

21

60.00%

0.023+

Diabetes Mellitus

15

32.61%

11

31.43%

0.910+

Congestive heart failure

17

36.96%

5

14.29%

0.023+

Coronary artery disease

15

32.61%

9

25.71%

0.501+

Chronic renal failure

4

8.70%

2

5.71%

0.612+

Chronic obstructive pulmonary disease + Asthma

24

52.17%

17

48.57%

0.748+

Cerebrovascular accident

5

10.87%

7

20.00%

0.252+

Chronic kidney disease

2

4.35%

3

8.57%

0.434+

Alzheimer’s

3

6.52%

one

2.86%

0.451ǂ

Malignity

3

6.52%

2

5.71%

0.881+

Under The Mask Spo2

88.46 ± 5.55

78.4 ± 10.97

0.0001*

Respiration Rate

38.28 ± 4.55

38.63 ± 5.35

0.754*

RASS Agitation Score

2.17 ± 0.68

2.66 ± 0.73

0.003*

A second administration of ketamine necessary?

No

46

100.00%

one

2.86%

0.0001 ǂ

Yes

0

0.00%

34

97.14%

Adverse effect of ketamine

No

39

84.78%

33

94.29%

0.178+

Yes

7

15.22%

2

5.71%

  1. *Independent t test + Chi-square test ǂFisher’s Reality Test