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Table 3 Logistic regression model for factors associated with 72 h. Return to ED among

From: Factors associated with early return visits to the emergency department in patients with vaso-occlusive crisis

 

Univariate

Multivariable

uOR

95%CI

P value

aOR

95%CI

P value

Age (years)

1

0.96 to 1.04

0.927

-

-

-

Sex

      

Male

Ref

     

Female

0.80

0.38 to 1.68

0.548

-

-

-

Has Comorbidities

1.73

0.82 to 3.65

0.149

1.41

0.57 to 3.52

0.459

Has History of transfusion exchange

0.95

0.45 to 1.99

0.890

-

-

-

Compliant on Hydroxyurea*

0.77

0.37 to 1.60

0.480

-

-

-

Number of ED visits

      

1–10

Ref

     

11–20

0.98

0.37 to 2.57

0.959

-

-

-

> 20

1.2

0.51 to 2.82

0.681

-

-

-

Previous admissions

      

0

Ref

     

1–3

0.88

0.21 to 3.64

0.854

-

-

-

4–10

1.58

0.39 to 6.28

0.520

-

-

-

> 10

1.02

0.25 to 4.12

0.977

-

-

-

Opioid given

0.75

0.22 to 2.62

0.655

-

-

-

Time to first opioid dose (minutes)

0.99

0.99 to 0.99

0.015

0.99

0.99 to 0.99

0.012

WBC (x103cells/µl)

1.01

0.93 to 1.09

0.843

-

-

-

Hb (g/dL)

1.21

0.96 to 1.52

0.100

1.30

0.99 to 1.71

0.061

MCV (fL)

1

0.97 to 1.03

0.905

-

-

-

PLT (x103cells/µl)

0.99

0.99 to 1.00

0.464

-

-

-

Total bilirubin (µmol/L)

1

0.99 to 1.02

0.402

-

-

-

Direct bilirubin (µmol/L)

1.05

0.99 to 1.11

0.078

1.07

1.01 to 1.15

0.021

  1. uOR: Unadjusted odds ratio, aOR: Adjusted odds ratio, CI: Confidence interval, Statistical significance at P value < 0.05. *Includes self-reported non-compliant and not prescribed hydroxyurea